RNA Details
Disease Name
kidney diseases
Tissue
kidney
RNA Symbol
mir-155
RNA ID
RNA Type
miRNA
Alteration Pattern
up regulation
Species
homo sapiens
Detection Methods
NA
Target
NA
Pathway
TGF-BETA SIGNALING PATHWAY
PubMed ID
Title
Hypoxia-induced microRNA-155 promotes fibrosis in proximal tubule cells
Year
2015
Function
"Hypoxia-induced miR-155 was a pro-fibrotic cytokine which was positively regulated by HIf-1alfa, but also revealed that miR-155 promoted the fibrosis of proximal tubule cells by regulating both TGF-beta and the process of epithelial-mesenchymal transition (EMT) under hypoxia."